Our platform
An all-electric label-free protein analysis platform, engineered for convenience
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Our platform
An all-electric label-free protein analysis platform, engineered for convenience
Run a label-free assay in the comfort of your own bench. No more waiting for results from a dedicated analytics lab.
Convenient
Fully automated & flexible
Fast results
Quad-sensor setup
Affordable
No optical components
Low maintenance
Reduced downtime and costs
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Key features of the HexagonFab Bolt
Quad-sensor setup
Nanomolar sensitivity
Concentration, affinity, kinetics
Label-free detection
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Intuitive all-in-one software
Molecule size indifferent
Low maintenance
All-electric detection without optical components
Most analytical instruments for protein characterisation use optical technology and thus require complex and bulky equipment that leads to high running costs and maintenance schedules. Our approach is based on an all-electric detection - no more optical components! The microchip at the heart of the sensor is capable of analysing proteins and their interactions in a simple, affordable, benchtop plug & play plate reader - HexagonFab Bolt.
Driven by advances in nanotechnology, microelectronics and advanced algorithms, we have developed an entirely different approach. Our goal is to democratise protein characterisation, by making it significantly more affordable, easier to use and faster than ever before.
Bolt’s simple quad-sensor format is compatible with standard 96-well plates and the intuitive software gives you the flexibility that you need in your everyday experiments.
The Sensor
The Sensor
Our sensor, a stamp sized microchip, detects the electrical charge of biomolecules. Binding events are directly translated into a digital signal. We are building on the technology driving field effect transistors (FET), the device that has enabled the computational revolution of the 20th century, and combined it with the most recent advances in nanotechnology to create the bio-FET.
A single atomic layer
A single atomic layer
The bio-FET is driven by a single atomic layer of a carbon crystal - graphene. Changes in the electrical charges in its environment affect the electrical properties of the graphene layer. Thus, we are able to detect minute electrical charge changes allowing the detection of biomolecule binding with high precision.
Powered by world-leading research
Powered by world-leading research
Building on years of research at the University of Cambridge and supported by InnovateUK, Wellcome Trust, and Royal Academy of Engineering, we have developed the methods to produce and manipulate these atomically thin crystals with the required precision.
Together with a method for stable and fast surface functionalisation, cutting-edge engineering and intuitive software, we are bringing new tools to advance the research and development of novel therapeutics.